The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells
نویسندگان
چکیده
منابع مشابه
The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells.
Germ cells and adult stem cells maintain tissue homeostasis through a finely tuned program of responses to both physiological and stress-related signals. PLZF (Promyelocytic Leukemia Zinc Finger protein), a member of the POK family of transcription factors, acts as an epigenetic regulator of stem cell maintenance in germ cells and haematopoietic stem cells. We identified L1 retrotransposons as ...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 2013
ISSN: 0261-4189,1460-2075
DOI: 10.1038/emboj.2013.118